What is POLYSORB® isosorbide impact on polymer glass transition temperature (Tg)?
Thanks to its original molecular design, POLYSORB® isosorbide often increase polymer Tg.
How can POLYSORB® isosorbide contribute to replace standard polycarbonate?
With such improvement, they can pretend to be a BPA-free, safe plastic alternative to standard polycarbonate.
Are POLYSORB® isosorbide-based polymers UV resistant?
Thanks to its non-aromatic (cycloaliphatic) structure, POLYSORB® isosorbide does not introduce into polymers UV sensitive bonds, enabling higher UV resistance to plastics.
What is the difference between standard polycarbonate and POLYSORB® isosorbide-based polycarbonate?
Is POLYSORB® isosorbide suitable for polyester resin modification?
Is POLYSORB® ID a bio-based plasticizer?
What is the resin identification code (RIC) for isosorbide-based plastics?
Does the "7" resin identification code on plastic mean they contain POLYSORB® isosorbide?
What can be considered as a POLYSORB® isosorbide derivative?
POLYSORB® isosorbide has a unique diol structure that enables molecule grafting or polymerisation.
All compounds based on chemical modification of POLYSORB® isosorbide can be qualified as isosorbide derivative.
Are POLYSORB® isosorbide-based polymers considered as bio-based polymers?
However, polymers based on isosorbide are produced with other co-monomers.
It is recommended to contact the resin manufacturer to have more information of final bio-based content of the material.
Is POLYSORB® isosorbide a bio-based monomer?
What is POLYSORB® isosorbide?
POLYSORB® isosorbide is a cycloaliphatic monomer obtained from sorbitol dehydratation.
Sorbitol is a polyol obtained from glucose, the starch monomer.
Starch is the main component of plant-based raw materials such as maize, wheat,…
Is POLYSORB® isosorbide a chain extender?
What is a chain extender?
A chain extender is a short chain diol used in polyurethane-based thermoplastics (TPU) to create hard blocks.
TPU special properties are highly linked to the presence of such blocks.
Do Roquette APIs conform to ICHQ7A?
The implementation of the new European Pharmaceutical Directive (2004/27) have come into force on October 30, 2005. After that, each Active Pharmaceutical Ingredient will have to follow Good Manufacturing Practices according to the International ICHQ7A reference system. Roquette is therefore preparing to apply this quality reference system to its active ingredients.
What documentation is available for the CTD (Common Technical Document)?
GMP, or Good Manufacturing Practices, are a set of official production standards and as such only make sense when the appropriate reference is indicated. Probably the most widely recognised GMP standards for active ingredients are the ones defined by the US FDA under legislation 21 CFR, part 210-211. For instance, ROQUETTE’s LYCADEX PF has been assessed on a repeated occasions and has met these standards. However, there are other institutions that have set different GMP guidelines, such as WHO and IPEC. The question of GMP certification has to be considered in the context of the specific product and local regulatory requirements.
For more information on this issue, please contact us or your local representative.